產(chǎn)品名	鈣離子載體A23187
別名	離子載體(鈣鎂鹽混合物);鈣離子載體 A23187;鈣離子載體A23187(鈣鎂混合鹽);卡西霉素;離子載體;抗生素 A 23187;鈣離子載體
英文名	Calcium Ionophore A23187
CAS號	52665-69-7
分子式	C29H37N3O6
分子量	523.620588064194
EINECS編號	258-084-1
MDL號

CAS：52665-69-7
分子式C29H37N3O6  分子量523.62
應(yīng)用范圍： 
高選擇性鈣離子載體增強(qiáng)對 NMDA 非使君子氨酸的響應(yīng)。在細(xì)胞培養(yǎng)中，通過鈣調(diào)素依賴結(jié)構(gòu)型一氧化氮合酶刺激一氧化氮的生成。
與二價(jià)陽離子形成穩(wěn)定絡(luò)合物的移動(dòng)離子載體。用于增加細(xì)胞內(nèi)Ca 2+水平。還充當(dāng)氧化磷酸化的解偶聯(lián)劑和線粒體ATPase活性的抑制劑
溶解性： Soluble in water (Partly miscible), DMSO (1 mg/ml), and DMF (10 mg/ml).
如果有可能，您盡量在同一天配置溶液，并在當(dāng)天使用完它。但是，如果您需要預(yù)先配制儲備溶液，我們建議您將溶液等份保存在-20°C的
密封小瓶中。通常，它們最多可以使用一個(gè)月。在使用前和打開樣品瓶之前，我們建議您讓您的產(chǎn)品在室溫下平衡至少1小時(shí)

保存：-20℃避光保存

A23187 is an ionophore, highly selective for Ca2+, that allows for divalent cations to move across the membranes which are usually
impermeable to them. The compound was originally isolated from Streptomyces chartreusensis for use as an antibiotic but has been
shown to have weak in vitro antimicrobial activity against fungi and gram positive bacteria. Because of its ability to increase intracellular
calcium levels of intact cells, it is used in studies of intracellular Ca2+ mediated events. A23187 has been observed to induce cell activation,
differentiation or proliferation. In vitro experimentation has shown A23187 to boost ROS generation and platelet fragmentation